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Professor Division of Gynecologic Oncology Department of Obstetrics and Gynecology Creighton University School of Medicine at St. Joseph’s Hospital and Medical Center, a member of Catholic Healthcare West 500 W. Thomas Road, Suite 660 Phoenix, AZ 85013 (USA) Tel #: (602) 406-6000 Fax #: 602-406-9921 Email: Bradley.monk@chw.edu Biographical Summary Dr. Monk received his medical degree from the University of Arizona in 1988 where he graduated at the top of his class. He then underwent training in Obstetrics and Gynecology at the University of California, Los Angeles between 1988 and 1992, and Gynecologic Oncology at the University of California Irvine (UCI) between 1992 and 1995. In 1995, he was appointed the Director of Gynecology Oncology at Texas Tech University and Associate Director of the Southwest Cancer Center where he served until 1998. Since 1998, he has been a member of the faculty at UCI where he currently is Associate Professor (with Tenure). He is board certified in both Obstetrics and Gynecology and Gynecologic Oncology. He is a fellow of the American College of Surgeons and the American College of Obstetricians and Gynecologists. He is also an active full member of the Society of Gynecologic Oncologists, American Society of Clinical Oncology, and the American Association of Cancer Research. Dr. Monk has been an Investigator for the Gynecologic Oncology Group (GOG) since 1995 and is the Chair of the Cervical Committee along with serving on the Tissue Utilization and Publications Committees. He is the Co-Principal Investigator for the GOG at UCI and Study Chair for both group wide phase III trials in cervical carcinoma and also serves as the study chair or co-chair for seven other trials investigating new therapies in cervical and ovarian cancer. Dr. Monk has received career development funding (K-23) from the National Cancer Institute (NCI) to investigate new strategies against HPV related illnesses and, in addition, is funded by the NCI to study therapeutic HPV vaccines. Dr. Monk has over 90 peer-review publications predominantly dealing with the areas of cervical and ovarian cancer prevention, therapeutics as well as issues related to quality of life. He has also published fifteen book chapters and is on the Editorial Board for Gynecologic Oncology and The American Journal of Hematology/Oncology and is a past President of the Orange County OB-GYN Society.
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Professeur honoraire de l’obstétrique et la Gynécologie et la Psychiatrie École d’université de Yale de la médecine New Haven, CT (Etats-Unis) Dr. Philip M. Sarrel, MD est actuellement professeur honoraire de l’obstétrique et la Gynécologie et la Psychiatrie à l’école d’université de Yale de la médecine à New Haven, le Connecticut. Il a été nommé au corps enseignant de Yale en 1969 et est resté chez Yale dans toute sa carrière, se levant au rang du plein professeur en 1988. Après réception de sa licence de l’université de Dartmouth à Hannovre, au New Hampshire, et son degré médical d’école d’université de New York de la médecine à New York, Dr. Sarrel a rempli son internat à l’hôpital de Sinai de bâti à New York et à sa résidence en obstétrique et Gynécologie au centre médical d’Yale-Nouvel asile à New Haven. Après sa nomination au corps enseignant de Yale en 1969, avec Lorna Sarrel, il a fondé le sexe de Yale conseillant le service. En 1971, lui et Mme Sarrel ont été formés dans la thérapie de sexe par William Masters et Virginie Johnson et en 1975-1976 ; Dr. Sarrel a reçu une récompense de disciple de faculté de fondation de Macy pendant une année à l’université d’Oxford en Angleterre, où il a travaillé avec John Bancroft dans le département de la Psychiatrie. En 1976, Dr. Sarrel a commencé le régime de ménopause de Yale et en 1982-1983, il a consacré une année sabbatical à l’étude de la ménopause fonctionnant avec Dr. Malcolm Whitehead aux Rois College Hospital à Londres. Il a été promu au rang du plein professeur en 1988 chez Yale. Dans 1989-1990 sa nomination dans la médecine cardiaque à l’institut national de coeur et de poumon à Londres a permis une année de la recherche en matière de cardiologie dans les effets des hormones ovariennes sur le fonctionnement artériel. En outre en 1990, Dr. Sarrel a commencé sa tenure comme Codirectrice de la clinique de Yale Neuro-gynécologie, qui continue aujourd’hui. Par année 1996-1997 d’universitaire, une nomination en tant que professeur visitant dans le département de la médecine interne à l’hôpital Colombie-Presbytérien à New York a permis une année d’étude consacrée à l’arrangement les actions des androgènes. Il a servi de conseiller au centre pour la médecine alternative au centre médical Colombie-Presbytérien, New York, NY, depuis 1997. Il a également servi de conseiller au centre pour la médecine alternative à l’hôpital d’Yale-Griffon, Derby, le Connecticut depuis 1998, et depuis 2000 avait servi le conseiller dans le département de la médecine préventive à l’hôpital d’Yale-Griffon. Chez Yale, Dr. Sarrel a été Codirecteur du sexe conseillant le service depuis 1969 et le directeur du régime d’étude de moitié de la vie depuis 1984. Dr. Sarrel est l’auteur ou le co-auteur plus de de 200 articles et chapitres médicaux pour les textes médicaux et est également le co-auteur de six manuels liés à la ménopause et au comportement et à la réponse sexuels d’arrangement. Il a été le bénéficiaire de quatre concessions de recherches des instituts nationaux de la santé aussi bien que beaucoup d’autres concessions de recherches des fondations et de l’industrie pharmaceutique. Sa recherche pendant les 17 dernières années s’est concentrée sur des études des effets artériels des hormones et des éditions liées au sexe et au vieillissement. Il est actuellement impliqué dans les études des interventions diététiques, et SERMs et phytoestrogens et leurs effets sur la cellule endothéliale fonctionnent. Il était l’un des Co-chercheurs de l’oestrogène des femmes pour l’épreuve de prévention de course financée par les instituts nationaux de la maladie neurologique et la course. Dr. Sarrel est actuellement le rédacteur de MATURITAS, le journal de la société internationale de ménopause ; Ménopause, le journal de la société américaine du nord de ménopause ; le journal de la recherche de sexe ; le journal du sexe et de la thérapie matrimoniale ; et le journal de la médecine Genre-Spécifique. Il est également un critique de manuscrit pour le journal de la Nouvelle Angleterre de la médecine, le journal américain de l’obstétrique et de la Gynécologie, des révisions Endocriniennes, la recherche cardiovasculaire, le journal de l’endocrinologie et du métabolisme cliniques, et le journal américain de la cardiologie.
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Titre Administratif: Chef, Directeur De Pathologie, CytopathologyNew England Pathology Associates, P.C. Éducation: Étudiant préparant une licence: Bates College, B.S., 1968 École Médicale: University of Connecticut School of Medicine, M.D., 1976 Formation Doctorale De Poteau: Internats et résidences: University of Rochester Medical Center, Rochester, NY, Residency in AP Strong Memorial Hospital 1976-1978 Residency in AP Hartford Hospital, Hartford, CT 1978-1979 Licensure et certification: American Board of Medical Examiners- 1972 Massachusetts Medical License No. 44997- 10/79 American Board of Pathology (Anatomic Pathology)- 6/82 American Board of Pathology (Cytopathology)- 7/97 Rendez-vous Scolaires: Professeur Auxiliaire(Clinical), Department of Pathology, Tufts University School of Medicine – March 2000 Rendez-vous D’Hôpital: 2002-Present Chef de pathologie Mercy Medical Center 2002-Present Directeur de Cytopath New England Pathology Associates, P.C. 1997-2002 Pathologiste D’Associé Département de pathologie, Baystate Medical Center, Springfield, MA 1989-1992 Chef de Cytopathology Life Laboratories Mercy Hospital, Springfield, MA 1979-1988 Chef d’aiguille fine Aspirates and Autopsy Service Baystate Medical Center, Springfield, MA Récompenses et honneurs: 1971 National Competition for Cytotechnologist Research (2nd) American Society of Cytopathology 1976 Outstanding Student in Pathology Univ. of Connecticut School of Medicine 1978 National Competition for Resident Research (2nd) American Society of Cytopathology 1979 Resident Research Competition (2nd) New England Cancer Society Professional Societies: 1992-Present American Medical Association 1992-Present Massachusetts Medical Association 1992-Present Hampden County Medical Society 1992-Present American Society of Cytotechnology 1992-Present New Hampshire/Vermont Society of Cytology 1996-Present American Pathology Foundation Tâches du Comité dans les sociétés professionnelles: Comité directeur et le Comité de programme, American Pathology Foundation Intérêts Principaux De Recherches: Cytopathology – Aspiration Fine D’Aiguille; Préparations Fluide-Basées De Monocouche Responsabilités D’Enseignement: Membre de corps enseignant de Baystate Medical Center Le département du programme de résidence de pathologie et la camaraderie de Cytopathology programment responsable d’enseigner la cytologie et l’aspiration fine d’aiguille aux résidants de pathologie et aux camarades aînés de Cytopathology. Appui De Recherches: 1. Titre: A Multi-Center Clinical Trial to Demonstrate the Utility of the ThinPrep 3000© Processor™ for the Preparation of ThinPrep Slides Agence De Placement: Cytyc Corporation Quantité: $75,000 Rôle: Investigateur Principal 2. Titre: Multi-Center Trial Evaluating the Primary Screening Capability of the ThinPrep™ Imaging System Agence De Placement: Cytyc Corporation Quantité: $52, 000 Rôle: Investigateur Principal Bureaux de rédaction et activité: Rédacteur, APF Review (American Pathology Foundation) Service Militaire: 10/68-8/72 Unites States Army; Honorable Discharge Service De la Communauté: Président, Board of Health Ludlow, MA Médecin D’École Ludlow, MA Bibliographie: Articles 1. March DE, Walker MT, Bur M, Coughlin BF, Dziura B, Lorenzana R, Makari-Judson G: Touch-Preparation Cytology of Breast Core Biopsy Specimens: Accuracy in Predicting Benign or Malignant Core Histology, 1999; Acad Radiol 6(6):333-338. 2. Richard K, Dziura B, Hornish A: Cell Block Preparation as a Complementary Diagnostic Technique to Fluid-Based Monolayer Cervicovaginal Specimens, 1999; Acta Cytol 43(1):69-73. 3. Dziura B, Beith K: Improved ASCUS Diagnosis: Clinical and Financial Implication for Follow-up Care. OB GYN supplemental to Ob. Gyn. News, 1999. 4. Nicastri G, Reed W, Dziura B: The Accuracy of Malignant Diagnoses Established by Fine Needle Aspiration Cytologic Procedures of Mammary Masses. Surg Gynecol Obstet, 1991;72(6):457-60. 5. Dachs R, Clement RE, Dziura B, Berman J: A Paraprosthetic-Enteric Fistula Associated With A Duodenal Tumor. Ann Vasc Surg, 1990;4(1):65-8. 6. Dziura RB: Fine Needle Aspiration of the Lung: A Pathologist’s Perspective. J Thorac Imaging, 1987;2(2):49-51. 7. Dziura B: Fine Needle Aspiration of the Breast: Intraductal Hyperplasia vs Ductal Carcinoma. Acta Cytol, 1979;23(4):332-340. 8. Dziura B, Bonfiglio T: Needle Cytology of the Breast. A Quantitative and Qualitative Study of the Cells of Benign and Malignant Ductal Neoplasia. Acta Cytol, 1979;23(4)332-40. 9. Dziura B, Otis R, Hukill P, Goldblatt P, Damjanov I: Gastric Brushing Cytology: An Analysis of Cells From Benign and Malignant Ulcers. Acta Cytol, 1977;21(2):187-90. 10. Cooney W, Dziura B, Harper R, Nash G: The Cytology of Sputum From Thermally Injured Patients. Acta Cytol, 1972;16:433-437. Résumés Édités: 1. Dziura B: Comparison of the ThinPrep Pap With the Detection of Glandular Abnormalities. Acta Cytol, 1999;43(5):902. 2. Dziura B: Morphologic Evaluation of Increased Detection of High Grade SIL With the ThinPrep Pap. Acta Cytol, 1998;42(5):1241. 3. Dziura B: Evaluation of the Effect of the ThinPrep Pap on the Diagnosis of ASCUS and Its’ Financial Implications in Follow-Up Care. Acta Cytol, 1998;42(5):1244. Autre: 1. Dziura B: Mediastinal Fine Needle Aspiration of Metastatic Nonsemenomatous Testicular Germ Cell Tumor. A.S.C.P. Check Sample, May, 1987. Conférences/Présentations Invitées: 2001 Workshop: ASCUS and the ThinPrep Pap New Jersey Society of Cytology 2001 The ThinPrep Pap in the Detection of Gynecologic Malignancies Baystate Medical Center Cytopathology Seminar 2001 Advances in Cervical Cancer Screening Southern Main Medical Center Bangor, ME 2001 Advances in Cervical Cancer Screening New Haven Area OB/GYN New Haven, CT 2000 Workshop: Advanced Thin Prep Morphology Manchester, NH 2000 Workshop: Advanced Thin Prep Morphology Philadelphia, PA 2000 Workshop: Advanced Thin Prep Morphology Manchester, CT 2000 Workshop: Advanced Thin Prep Morphology Boston, MA 2000 Advances in Cervical Cancer Screening Newton Wellesley Hospital Newton, MA 2000 Advances in Cervical Cancer Screening Ann Arbor Area OB/GYN Ann Arbor, MI 2000 Advances in Cervical Cancer Screening Minneapolis/St. Paul Area OB/GYN St. Paul, MI 2000 Advances in Cervical Cancer Screening Tulsa Area OB/GYN Tulsa, OK 2000 Advances in Cervical Cancer Screening Rochester Area OB/GYN Rochester, NY 1999 Selling Anatomic Pathology Services to Physician Offices: Using the Pathologist on the Marketing Team. Executive War College on Laboratory and Pathology Management New Orleans, LA 1999 Marketing Anatomic Pathology to Physician’s Offices Executive War College on Laboratory and Pathology Management New Orleans, LA 1999 Fine Needle Aspiration Biopsy of Difficult and Unusual Breast Lesions Presented at the Vermont/New Hampshire Cytology Society Bartlett, NH 1999 An Employer’s Eye View of the Cytotechnology Graduate – What We are Looking for in a New Hire Society of Cytology Educators of the Northeast Pittsfield, MA 1999 ThinPrep Potpourri 16th Annual Baystate Medical Center Cytopathology Workshop Springfield, MA 1999 Advances in Cervical Cancer Screening Tulsa Area OB/GYN Tulsa, OK 1999 Advances in Cervical Cancer Screening Glens Falls Hospital Glens Falls, NY 1998 Advances in Cervical Cancer Screening Nashville Area OB/GYN Nashville, TN 1998 Cytomorphology in the Gynecologic ThinPrep Pap Present at the 15th Annual Baystate Medical Center Cytopathology Workshop Springfield, MA 1998 Advances in Cervical Cancer Screening Pittsburgh Area OB/GYN Pittsburgh, PA 1998 Advances in Cervical Cancer Screening Littleton General Hospital Littleton, NH 1998 Cell Block Preparation as a Complementary Diagnostic Technique to Fluid-Based Monolayer Cervicovaginal Specimens American Society of Cytopathology Nashville, TN 1993 The ThinPrep Experience in the Laboratory Baystate Medical Center Cytopathology Seminar 1991 The Use of Fine Needle Aspiration of the Breast in the Management of Nonpalpable Lesions 10th Annual State of the Art Cytopathology Seminar 1990 Fine Needle Aspiration of the Breast – Problems and Pitfalls New Hampshire/Vermont Society of Cytology 1987 Problems in Pulmonary Cytopathology Rhode Island Society of Cytology 1983, 1984, 1985 Workshop: Fine Needle Aspiration of the Lung American Society of Clinical Pathologists 1982, 1983, 1986 Workshop: Fine Needle Aspiration of the Lung Rhode Island Society of Cytology 1985 Workshop: Fine Needle Aspiration of the Lung Ohio Society of Cytology 1987 Fine Needle Aspiration of the Lung Maine Society of Cytology 1981 Cytology for Histotechs Connecticut Histology Society 1980 Workshop: Gynecologic Cytopathology Connecticut Society of Cytology 1979 The Causes of False Positive and Negative Diagnosis in Pulmonary Fine Needle Cytology New England Cancer Society 1978 Breast Needle Cytology: Intraductal Hyperplasia vs Ductal Carcinoma American Society of Cytology 1971 Sputum Cytology of Thermally Injured Patients American Society of Cytology
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Treasurer The Women’s Health and Education Center (WHEC) The Women’s Health and Education Organization, Inc. (WHEO, Inc.) 11 West Elm Street West Townsend, MA 01474 Telephone: 508-361-3721 Fax: 508-525-4506 E-Mail:rslyons73156@hotmail.com Robert S. Lyons is Senior Vice President of Wealth Management with Merrill Lynch where he has been employed since 1998. Prior to joining Merrill Lynch, Mr. Lyons served as Executive Director of the University of Massachusetts Foundation for 10 years. He has more than thirty years of progressive experience in investments, finance, and accounting. Mr. Lyons is a Certified Financial Planner (CFP), Chartered Retirement Planning Counselor (CRPC), has an undergraduate degree in accounting, and an MBA from the University of Massachusetts Amherst. He participates in numerous community activities, and resides in Townsend, MA and Harwich, MA with his wife and three children. Robert has been financial adviser for The Women’s Health and Education Center (WHEC) and The Women’s Health and Education Organization, Inc. (WHEO, Inc.) since 2008.
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Senior Advisor in Health Promotion Leader, Urban Health and Health Determinants Team Area for Sustainable Development and Environmental Health Pan American Health Organization (PAHO) 525 23rd Street, NW Washington, DC 20037 Phone: 202 974-3969 Fax: 202 974-3645 e-mail: ricemari@paho.org Marilyn Rice is Senior Advisor in Health Promotion and Coordinator of the Urban Health and Determinants of Health Team for the Area of Sustainable Development and Environmental Health for the Pan American Health Organization (PAHO/WHO). She has over 30 years of experience working in a multi-cultural, multi-lingual environment, often playing the role of a facilitator to help ensure clear communication and collaborative efforts in developing and implementing initiatives. She has done extensive work to support systematic evaluation and documentation of health education and promotion experiences in countries throughout the world and she coordinated and oriented technical cooperation activities in the areas of health promotion, social determinants of health, urban health and development, community mobilization, and implementation of healthy public policies. She has worked for PAHO for 22 years and the Global Office of the World Health Organization (WHO) for 7. She has also held the position of Project Director of the National Resource Center for Prevention of Perinatal Abuse of Alcohol and Other Drugs and Branch Chief of the Perinatal Branch for the US Center for Substance Abuse Prevention (part of the US Department of Health and Human Services). She holds a degree in sociology and masters training in public health and health education. She is known throughout the world for her work in community development, social mobilization, health promotion and education, as well as for her leadership in the emerging field of urban health. She has been very active in the International Union for Health Promotion and Education (IUHPE), serving multiple terms as Regional Director, and she currently is the Regional Vice President for the North American Regional Office (NARO) and sits on the Global and NARO Boards. Additionally, she is the Chair of Society of Public Health Education’s (SOPHE) International and Cross-Cultural Health (ICCH) Community of Practice and as a result she also sits on the SOPHE Board. She is on the editorial board of numerous peer review journals in the fields of health promotion and education. More specifically, Marilyn Rice’s experience includes: Extensive experience in leading and managing the design and monitoring of new projects through promoting team work with a diverse group of professionals, and developed long-range strategies and objectives through consensus-building in initiatives focused on but not limited to the following areas: maternal and child health; reproductive health and family planning; gender sensitive health and development initiatives; demonstration projects addressing pregnant and postpartum women and infants exposed to alcohol and other drugs; participatory action planning and evaluation in health promotion and education, especially in local development priorities and in reproductive health; nutrition education; participatory education in health; research projects in health promotion/education and community participation, and in alcohol and other drug use; school-based health education; and disaster preparedness and the community’s participation Creating strategies, analytical models and methodologies for the planning and evaluation of public health initiatives Providing technical assistance and advice to countries throughout the world Writing state-of-the-art documents and guidelines in techniques for planning, implementing, monitoring and evaluating programs Developing training manuals and materials from entire face to face and virtual courses to supplemental electronic teaching and audio visual materials Drafting and securing approval from the Ministers of Health from countries throughout the Americas for position papers, as well as resolutions to generate cooperative implementation of PAHO and WHO programs by these governments Coordinating collaboration with a diverse group of professionals from United Nations, intra-country, national, regional and local agencies, universities, schools of public health, community organizations and professional societies Delivering numerous public speeches, presentations, briefings, lectures and seminars to audiences – in English, Spanish, Portuguese and French for government officials and/or for community leaders
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12 October, 2002 Mr. Paul Hoeffel Chief, NGO Section United Nations New York, NY 10017 Dear Sir: Please accept this letter of recommendation for the Women’s Health and Education Center of Springfield, Massachusetts. I have met with Dr. Rita Luthra on several occasions and understand the mission of the Center. It is my judgment that the Center is well qualified to be an accredited NGO to the DPI of the United Nations. Dr. Luthra has attended and participated in meetings of the UNA/USA and the Connecticut Division of our national organization. The Center is developing a useful and ambitious worldwide ob/gyn information system. If you have any questions, I would be pleased to respond. Sincerely, Irving Stolberg President, Connecticut Division UNA/USA
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Dr. Neeraj Kohli, MD, MBA Directeur, Division d’Urogynecology Brigham and Women’s Hospital Professeur Auxiliaire Harvard Medical School Boston, Massachusetts, USA nkohli@partners.org Dr. Kohli est un chef nationalement identifié dans le domaine de la chirurgie pelvienne d’Urogynecology et de Reconstructive, se spécialisant dans le traitement du prolapsus pelvien, de l’incontinence urinaire, et de la chirurgie pelvienne avancée. Il a écrit plus de 100 articles scientifiques, chapitres de livre, abrégés sur recherches, présentations cliniques, et outils éducatifs de multimédia. Depuis replacer à Boston, il était précédemment le Co-Directeur de la Division de la chirurgie pelvienne d’Urogynecology et de Reconstructive à l’hôpital auburn de bâti, au directeur de la camaraderie dans Urogynecology, et au directeur d’Urogynecology au centre médical de Tifts Nouvelle Angleterre à Boston. Il est actuellement chef d’Urogynecology au Brigham et à l’hôpital des femmes à Boston. Dr. Kohli a reçu son degré d’étudiant préparant une licence dans sciences/economics médical en 1987 et puis son degré médical 1991 par le BA/md combiné programme médical de six ans à l’école d’université de Boston de la médecine. Après avoir terminé ses travaux scolaires, DR Kohli a suivi le programme de résidence d’Ob/Gyn à l’hôpital de Beth Israel, Boston, et a reçu un diplôme avec un intérêt spécial pour la chirurgie pelvienne. Il a alors écrit la camaraderie fortement considérée dans la chirurgie pelvienne d’Urogynecology et de Reconstructive au bon hôpital de Samaritan, Cincinnati, Ohio sous la formation de Dr. Mickey Karram, président précédent de la société américaine d’Urogynecologic. Après exécution de sa camaraderie, il est resté dessus à Cincinnati en tant que directeur d’associé du programme de Division et de camaraderie, se concentrant sur enseigner, recherche, et pratique clinique. Il est retourné de nouveau à Boston à l’hôpital auburn de Beth Israel Hospital/Mount en juillet 1999. Pendant son retour initial vers Boston, il a accompli le programme de MBA de directeur à l’école du nord-ouest de Kellogg de la gestion Chicago, l’Illinois, recevant un diplôme avec des honneurs en 2002. L’intérêt courant de Dr. Kohli incluent d’une façon minimum la chirurgie pelvienne invahissante et les technologies de pointe pour le traitement de l’incontinence de prolapsus, et la douleur pelvienne. Ses beaucoup d’intérêts de recherches incluent l’coût-efficacité des techniques chirurgicales d’une façon minimum invahissantes, des facteurs de risque obstétriques pour le dysfonctionnement pelvien de plancher, et de l’application clinique de l’essai urodynamic. Il est activement impliqué dans l’enseignement des étudiants en médecine, des résidants, et des camarades chez les collègues médicaux de système scolaire et de médecin de Harvard dans tout le pays. Il est actuellement un conseiller scientifique pour Boston scientifique, Johnson et Johnson, barde de CR, aussi bien que plusieurs petites compagnies médicales de démarrage de technologie.
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General Manager & Treasurer eclecTechs™, LLC 22 Cherry Street Westfield, MA 01060 info@eclecTechs.com www.eclecTechs.com Barbara has been the General Manager at eclecTechs since 1998. eclecTechs offers many Internet services, including Web Design, Programming, Networking and Consulting. eclecTechs also offers DSL and web hosting at reasonable rates. Barbara received a degree in Accounting from The University of Massachusetts in 1989.
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Professor of Obstetrics and Gynecology Chief, Division of Maternal-Fetal Medicine University of Utah Health Sciences Center (UUHSC) 30 North 1900 East SOM 2B200 Salt Lake City, UT 84132 (USA) Tel: 801-585-5156 Fax: 801-585-2594 E-mail: robert.silver@hsc.utah.edu Education and Training: INSTITUTION AND LOCATION DEGREE YEAR (s) FIELD OF STUDY University of Pennsylvania, Philadelphia, PA BA 1982 Microbiology Medical College of Pennsylvania, Philadelphia, PA MD 1986 Medicine University of Colorado Health Sciences Center, Denver, CO Residency 1986-1990 Obstetrics and Gynecology University of Utah Health Sciences Center (UUHSC), Salt Lake City, UT Fellowship 1990-1994 Maternal-Fetal Medicine A. Positions and Honors Positions 1990-1991 Clinical Instructor, Department of Ob/Gyn, UUHSC, SLC, UT 1992-1994 Instructor, Department of Ob/Gyn, UUHSC, SLC, UT 1994-1998 Assistant Professor, Department of Ob/Gyn, UUHSC, SLC, UT 1998-2006 Associate Professor with tenure, Department of Ob/Gyn, UUHSC, SLC, UT 2006-present Professor with tenure, Department of Ob/Gyn, UUHSC, SLC , UT 1995-2003 Residency Director, Department of Ob/Gyn, UUHSC, SLC, UT 2001-present Medical Director of Labor and Delivery, UUHSC, SLC, UT 2000-present Division Chief, Maternal Fetal Medicine, Department of Ob/Gyn, UUHSC, SLC, UT Honors 1985 Kurt Pauker Achievement Award for Excellence in Microbiology 1986 Alpha Omega Alpha 1993-1998 Research Scientist Development Program, National Institutes of Health 2000 Poster Award (best of session): IgA beta-2-glycoprotein-I Antibodies are Elevated in Women with Unexplained Recurrent Spontaneous Abortion and Unexplained Fetal Death, Society for Gynecologic Investigation 2001 Poster Award (best of session): Heparin-induced Thrombocytopenia is Rare in Pregnancy, Society of Perinatal Obstetricians 18th Annual Meeting 2003 Poster Award (best of meeting): Stillbirth in Utah from 1995-2001 B. Peer-Reviewed Publications Select peer-reviewed publications (in chronological order) Mitchell MD, Edwin SS, Lundin-Schiller S, Silver RM, Smotkin D, Trautman MS. (1993). Mechanism of interleukin-1 beta stimulation of human amnion prostaglandin biosynthesis: mediation via a novel inducible cyclooxygenase. Placenta 1993; 14:615-25. Edwin SS, Branch DW, Scott JR, Silver RM, Mitchell MD. Cyclosporin A attenuates increased prostaglandin and thromboxane production in response to various stimuli in human decidua. Am J Reprod Immunol 1993;30: 154-9. Silver RM, Draper ML, Scott JR, Lyon JL, Byrne SL, Ashwood EA, Branch DW. Unexplained elevations of maternal serum alpha-fetoprotein in women with antiphospholipid antibodies: A harbinger of fetal death. Obstet Gynecol 1993; 83:150-5. Silver RM, Draper ML, Scott JR, Lyon JL, Reading J, Branch DW. Clinical consequences of antiphospholipid antibodies: An historical cohort study. Obstet Gynecol, 1994;83:372-7. Mitchell MD, LaMarche S, Adamson S, Coulam C, Silver RM, Edwin SS. Regulation of intrauterine prostaglandin biosynthesis interactions between protein kinase C and interleukin 1Β. Prost Leuk EFA 1994;50:137-40. Silver RM, Edwin SS, Trautmna MS, Simmons DL, Branch DW, Dudley DJ, Mitchell MD. Bacterial lipopolysaccharide mediated fetal death: Production of a newly-recognized form of inducible cyclooxygenase (COX-2) in murine deciduas in response to lipopolysaccharide. J Clin Invest 1995;93:725-31. Silver RM, Pierangelli SS, Gharavai AE, Harris EN, Edwin SS, Salafia CM, Branch DW. Induction of high levels of anticardiolipin antibodies in mice by immunization with Β2-glycoprotein 1 does not cause fetal death. Am J Obstet Gynecol 1995;173L1410-5. Silver RM, Porter TF, van Leeuwen I, Coulam C, Jeng G, Scott JR, Branch DW. Anticardiolipin antibodies: Clinical consequences of low titers. Obstet Gynecol 1996;87:494-500. Oshiro BT, Silver RM, Scott JR, Yu H, Branch DW. Antiphospholipid antibodies and fetal death. Obstet Gynecol 1996;87:489-93. Edwin SS, Branch DW, Scott JR, Silver RM, Dudley DJ, Mitchell MD. Cyclosporin A inhibits prostaglandin E2 production by fetal amnion cells in response to various stimuli. Prostaglandins 1996;52:51-61. Branch DW, Silver RM. Criteria for antiphospholipid syndrome: early pregnancy loss, fetal loss, or recurrent pregnancy loss? Lupus 1996;5:409-13. Branch DW, Silver RM, Pierangeli SS, van Leeuwen I, Harris EN. Antiphospholipid antibodies other than lupus anticoagulant are not associated with recurrent pregnancy loss. Obstet Gyencol 1997;89:549-55. Silver RM, Edwin SS, Umar F, Dudley DJ, Branch DW, Mitchell MD. Bacterial lipopolysaccharide-mediate fetal death: The role of interleukin-1. Am J Obstet Gynecol 1997;176:544-9. Silver RM, Pierangeli SS, Edwin SS, Umar F, Harris EN, Scott JR, Branch DW. Pathogenic antibodies in women with obstetric features of antiphospholipid syndrome who test negative for lupus anticoagulant and anticardiolipin antibodies. Am J Obstet Gynecol 1997;176:628-33. Silver RM, Smith LA, Edwin SS, Oshiro BT, Scott JR, Branch DW. Variable effects of immunoglobulin G fractions from women with antiphospholipid antibodies on murine pregnancy. Am J Obstet Gynecol 1997;177:229-33. Coulam CB, Clark DA, Beer AE, Kutteh WH, Silver RM, Kwad J, Stephenson M. Current clinical options for diagnosis and treatment of recurrent spontaneous abortion. Am J Reprod Immunol 1997;38:57-74. Edwin SS, Mitchell MD, Silver RM, Branch DW, Dudley DJ. Ceramide stimulates prostaglandin production by human amnion and decidual cells J Soc Gynecol Invst 1997;4:274-8. Gharavi AE, Cucurull E, Tang H, Silver RM, Branch DW. Effect of antiphospholipid antibodies on beta-2-glycoprotein I-phospholipid interaction. Am J Reprod Immunol 1998;39:310-5. Kutteh WH, Rote NS, Silver RM. Antiphospholipid antibodies and reproduction. Am J Reprod Immunol 1999;41:133-154. Pregnancy loss study group (Branch DW, Druzin M, El-Sayed Y, Esplin MS, Hrager J, Peaceman AM, Silver RK, Silver RM, Spinnato J). A multicenter, controlled, pilot study of intravenous immune globulin treatment antiphospholipid syndrome in pregnancy. Am J Obstet Gynecol 2000;182:122-7. Van-Horn JT, Craven C, Ward K, Branch DW, Silver RM. Histologic features of gestational tissues from women with antiphospholipid and antiphospholipid-like syndromes. Placenta 2004;25:642-8. Ornoy A, Chen L, Silver RM, Mosmann TR, Miller RK. Maternal autoimmune diseases and immunologically-induced embryonic and feto-placental damage. Birth Defects Res Part A Clin Mol Teratol 2004;70:71-81. Frias AE, Luikenaar RA, Sullivan AE, Porter TF, Branch DW, Silver RM. Poor obstetric outcome in subsequent pregnancies in women with prior fetal death. Obstet Gynecol 2004;104:521-6. Sullivan AE, Silver RM, LaCoursiere DY, Porter TF, Branch DW. Does recurrent aneuploidy contribute to recurrent miscarriage? Obstet Gynecol 2004;10:784-8. Sullivan AE, Nelson L, Rice JA, Porter TF, Branch DW, Silver RM. The factor V Leiden and the G20210A prothrombin gene mutations are rare in women with fetal death. Am J Reprod Immunol 2005;54;1-4. Sullivan AE, Nelson L, Silver RM, Frias AE, Porter TF, Branch DW. The aryl hydrocarbon receptor nuclear tranlsocator gene polymorphism in patients with recurrent miscarriage. Am J Reprod Immunol 2006;55(1): 51-3 Silver RM, Landon MB, Rouse DC, Leveno JK, Spong CY, Thom EA, et al. Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol 2006;107(6): 1226-32. Silver RM. Fetal Death. Obstet Gynecol 2007;109(1):153-67. Silver RM, Varner MW, Reddy U, Goldenberg R, Pinar H, Conway D, Bukowski R, Carpenter M, Hogue C, Willinger M, Dudley D, Saade G, Stoll B. Work-up of stillbirth: a review of the evidence. Am J Obstet Gynecol 2007;196:433-44. Warren JE, Silver RM, Nelson L, Dalton J, Porter TF, Branch DW. Cervical insufficiency: a genetic condition? Collagen 1?1 intron SP1 and transforming growth factor-? ARG-25-PRO polymorphisms in women with cervical insufficiency. Obstet Gynecol 2007;110:619-24. Raju TN, Nelson KB, Ferriero D, Lynch JK; NICHD-NINDS Perinatal Stroke Workshop Participants. Pediatrics 2007;120:609-16. Holmgren C, Esplin MS, Hamblin S, Esplin MS, Molenda M, Silver RM. Evaluation of the use of anti-TNF-alpha in an LPS-induced murine model. J Reprod Immunol 2008; Epub, April 21. Silver RM. New anticoagulants and pregnancy. Obstet Gynecol 2008;112:419-20. Silver RM. Immune activation early in pregnancy: trouble down the road. Am J Obstet Gynecol 2008, 199;327-8. Holmgren C, Porter TF, Varner MW, Aagard K, Silver RM. Hyperemesis in pregnancy: A comparison of treatment strategies. Am J Obstet Gynecol, 2008;198:56e1-4. Turok DK, Gurtcheff S, Esplin MS, Shah M, Simonsen SE, Shah M, Trauscht-Van Horn J, Silver RM. Second trimester termination of pregnancy: A review by site and procedure type. Contraception 2008;77:155-61 Peltier MR, Faux DS, Hamblin SD, Cooper C, Silver RM, Esplin MS. Effect of aspirin treatment on TNF-? Production by women with a history of preterm birth. J Reprod Immunol 2009;80:109-14. Warren JE, Silver RM, Branch DW, Porter TF. Thromboprophylaxis and pregnancy outcomes in asymptomatic women with thrombophilias. Am J Obstet Gynecol 2009;200:281.e1-5. Warren JE, Nelson L, Esplin MS, Silver RM. Interleukin-10 polymorphisms and cervical insufficiency. Am J Obstet Gynecol 2009;201:372-4. Manuck TA, Eller AG, Esplin MS, Stoddard G, Varner MW, Silver RM. Outcomes of expectantly managed preterm premature rupture of membranes occurring ? 24 weeks gestation. Obstet Gynecol 2009;114:29-37. Reddy UM, Goldenberg R, Silver R, Smith GCS, Pauli RM, Wapner RJ, et al. Stillbirth classification: developing an international consensus for research: Executive summary of NICHD workshop. Obstet Gynecol 2009;114:901-14. Manuck TA, McLean, Varner MW, Silver RM. Preterm premature rupture of membranes: does the duration of latency influence neonatal outcome? Am J Obstet Gynecol 2009;201:414-6. Warren JE, Turok DK, Maxwell TM, Brothman AR, Silver RM. Array comparative genomic hybridization (aCGH) for genetic evaluation of fetal loss between 10 and 20 weeks gestation. Obstet Gynecol 2009;114:1093-1102. Clark EAS, Lacoursiere DY, Byrne JLB, Ponder R, Silver RM, Esplin MS. Reliability of fetal MCA velocity: a randomized controlled trial of sonographer training. J Ultrasound Med 2009;28:19-25. Grosvenor Eller A, Silver RM, Zempolich K, Soisson P, Simonson SE. Optimal management of placenta accreta. Br J Obstet Gynecol 2009;116:648-54. Peltier MR, Faux DS, Hamblin SD, Silver RM, Esplin MS. Cytokine production by peripheral blood mononuclear cells of women with a history of preterm birth. In press, J Reprod Immunol. Silver RM, Zhao Y, Spong C, Caritis SN, Sibai B, Wendel G Jr., et al. Prothrombin gene G20210A mutation and obstetric complications: a prospective cohort. In press, Obstet Gynecol. C. Research Support Ongoing Support NIH/NICHD 1U10HD063053-01 Preterm Birth in Nulliparous Women: An Understudied Population (Silver)12/01/2009-11/30/2014 This Network will design and execute a prospective, longitudinal cohort study of 10,000 nulliparous women. The research protocols developed will determine characteristics that influence and/or predict adverse pregnancy outcomes in nulliparous women including genetics, epigenetics, physiological response to pregnancy, interaction with environmental exposures, fetal growth and development, and placental development and function. Role: PI NIH/NICHD 3U10HD045944-05S2 Research on the Scope and Causes of Stillbirth in the United States (Silver)09/26/2003–07/31/2009NCX The major goals of this project are to develop a network of collaborating academic centers to study the extent and causes of stillbirth and to develop methods for stillbirth prevention. Role: PI NIH/NICHD HHSN267200603423C / N01DK63423 (Silver)09/30/2006-09/29/2011 The Effects of Aspirin in Gestation and Reproduction The purpose of this contract is to evaluate the effect of daily low-dose aspirin on all phases of reproduction beginning at preconception and continuing throughout pregnancy, including implantation and live births. Role: PI
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16 February, 1994 Dear Dr. Luthra, On behalf of the IYF Coordinator, I would like to acknowledge, with thanks, receipt of your letter to him of 9 February 1994. We are very pleased to learn that you have established close contacts with Dr. Belsey of WHO and have made good progress on your plans and activities on health and status of women in developing countries, as a specific contribution to the International Year of the Family. The IYF Coordinator and his Secretariat will continue to be of assistance whenever possible. As regards the proposed dates for the conference on the Year, kindly note that a major international event is planned to be held in Montreal from 12 to 15 October, held in cooperation with the IYF Secretariat, and on 18 October the General Assembly is scheduled to hold a special conference on families. I am attaching, by fax, relevant pages of the Calendar of events related to the Year, which you may find useful in your planning. A copy of the Calendar is sent by mail. I look forward to our continued and mutual beneficial cooperation. With best wishes, Yours sincerely, George Puthuppally Social Affairs Officer
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